SIOP-HRMB
International study for patients with high-risk medulloblastoma
Medulloblastoma is a malignant brain tumour. Treatment consists of a combination of surgery, radiotherapy, and chemotherapy. Improving treatment outcomes for patients with high-risk medulloblastoma (HR-MB) and minimising both short- and long-term side effects remain key priorities. HR-MB includes medulloblastomas of certain biological subgroups and those with metastases. Recognised treatment strategies vary between countries and clinics. These include various radiotherapy and chemotherapy regimens. It is not yet known which of these treatment options is the most effective. The aim of this study is to determine this through direct comparison.
Is this study suitable for my child’s condition?
Leukaemia, lymphoma and bone marrow disease
- Acute lymphoblastic leukemia (ALL)
- Acute myeloid leukemia (AML)
- Chronic myeloid leukemia (CML)
- Myelodysplastic syndrome (MDS)
- Severe aplastic anemia (SAA)
- Non-Hodgkin lymphoma
- Hodgkin lymphoma
- Other leukaemia, lymphoma and bone marrow disease
Brain and spinal cord tumors
- Low-grade glioma
- High-grade glioma
- Diffuse-intrinsic pontine glioma (DIPG) / Diffuse midline glioma (DMG)
- Medulloblastoma
- Atypical teratoid rhabdoid tumours (ATRT)
- Ependymoma
- Germ cell tumours / germinoma / nongerminomatous germ cell tumours / teratoma (brain / spinal cord)
- Craniopharyngioma
- Other brain tumours or spinal cord tumours
Solid tumors
- Wilms tumours / nephroblastoma
- Neuroblastoma
- Rhabdomyosarcoma
- Ewing sarcoma
- Osteosarcoma
- Rhabdoid tumours (other than brain or spinal cord)
- Other sarcoma
- Germ cell tumours (other than brain or spinal cord)
- Retinoblastoma
- Hepatoblastoma
- Other solid tumours
Study Information
What age range of children can participate?
From 5 years
Official Study Information
Questions? Please contact your medical team.
If you would like more information about a study, please speak to your child’s treating physician. They are your primary point of contact and can provide personalized advice and support. If no treatment team is currently in place, you can find general contact information for the study sites on the map below.
Treatment Centers with Open Study – Map & Overview
The map shows all treatment sites in Switzerland. Locations where the study is currently open are marked in blue. You can find contact details by clicking on the towns. The information on study sites is updated regularly. However, a study may occasionally open at a new site before this is reflected on the platform. If in doubt, please contact your treatment team or one of the listed clinics directly.
Aarau
KSA Kinderspital Aarau
Tellstrasse 25
Haus 9
5001 Aarau
Telefon: +41 62 838 49 41
E-Mail: kinderspital@ksa.ch
https://www.ksa.ch/de/kinderspital-aarau/aufenthalt-und-besuch-kinderspital
Pädiatrische Hämatologie und Onkologie
Telefon: +41 62 838 49 13
E-Mail: kinderonkologie@ksa.ch
Basel
Universitäts-Kinderspital beider Basel UKBB
Spitalstrasse 33
4056 Basel
+41 61 704 12 12
www.ukbb.ch
Bellinzona
Servizio di emato-oncologia pediatrica
Ospedale Regionale di Bellinzona
Via Athos Gallino 12
6500 Bellinzona
https://www.eoc.ch/specialita/pediatria.html
+41 91 811 89 77
ematooncologiapediatrica@eoc.ch
Bern
Inselspital, Universitätsspital Bern
Kinderklinik
Julie-von-Jenner-Haus
Freiburgstrasse 15
3010 Bern
Telefon: +41 31 632 04 61
https://kinderklinik.insel.ch/de/unser-angebot/onkologie/
Sekretariat Hämatonkologie
Telefon: +41 31 632 04 61
E-Mail: kinder.haematonkologie@insel.ch
Genève
HUG Hôpitaux Universitaires Genève
Département de la Femme, de l’Enfant et Adolescent (DFEA)
Service de Pédiatrie Générale
Hôpital des Enfants
Rue Willy-Donzé 6
1205 Genève
Téléphone: +41 22 372 40 00
https://enfants-ados.hug.ch/hopital-enfants
https://www.hug.ch/departement-femme-enfant-ado/services-medicaux
Unité d’Oncologie et Hématologie Pédiatrique (UOHP)
Téléphone: +41 22 372 47 31
https://enfants-ados.hug.ch/specialites-medicales-chirurgicales/oncologie-hematologie-pediatrique
Plateforme de recherche CANSEARCH en Oncologie et Hématologie pédiatrique,
Département de Pédiatrie, Gynécologie et Obstétrique
Université de Genève
Centre Médical
Téléphone: +41 79 553 61 00
Email : plateforme-cansearch@unige.ch
https://www.unige.ch/medecine/petri/groupes-de-recherche/907ansari
Lausanne
CHUV Centre Hospitalier Universitaire Vaudois
Service de pédiatrie – Département femme-mère-enfant
Hôpital des Enfants CHUV
Rue du Bugnon 50
1011 Lausanne
https://www.chuv.ch
Unité d’hématologie-oncologie pédiatrique (HOP)
Main phone : +41 21 314 35 90
Email: ped.pon@chuv.ch
https://www.chuv.ch/fr/dfme/dfme-home/enfants-famille/specialites-medicales/hematologie-oncologie-pediatrique/oncologie-pediatrique
Luzern
Luzerner Kantonsspital
Kinderspital Zentralschweiz
Haus 33
Spitalstrasse
6000 Luzern 16
Telefon: +41 41 205 31 66
https://www.luks.ch/standorte/standort-luzern/kinderspital/leistungsangebot-kinderspital/boesartige-erkrankungen-tumoren-bluterkrankungen-bei-kindern-und-jugendlichen
Kontakt Onkologie
Telefon: +41 41 205 31 86
kinderspital.ambi2west@luks.ch
St. Gallen
Stiftung Ostschweizer Kinderspital
Zentrum für Onkologie/ Hämatologie
Claudiusstrasse 6
9006 St. Gallen
https://www.kispisg.ch/de/fachbereiche/kompetenzen/onkologie
Telefon : + 41 71 243 70 43
Email: info.Onkologie-CRC@kispisg.ch
Zürich
Universitäts-Kinderspital Zürich –
Eleonorenstiftung
Lenggstrasse 30
8008 Zürich
https://www.kispi.uzh.ch
Sekretariat Onkologie
Telefon: +41 44 249 63 50
E-Mail: onkologie.sekretariat@kispi.uzh.ch